Patient Stories Transcript

VIDEO TRANSCRIPT

[DESCRIPTION]
Video opens on footsteps walking through a snowy forest, casting shadows in the snow. Michael’s signature and RECOVERY REWRITTEN appear on screen.

On-screen text:
RECOVERY REWRITTEN
Michael
This is my story of recovery with SUBLOCADE®

[SPEECH]
I couldn't stop myself. It got to a point where it felt like I split into 2 people. My name is Michael, and this is my story of recovery with SUBLOCADE®.

[DESCRIPTION]
Indication and select Important Safety Information appears over background of a forest scape.

On-screen text:
INDICATION
SUBLOCADE® (buprenorphine extended-release) injection, for subcutaneous use, CIII, is a prescription medicine used to treat adults with moderate to severe addiction (dependence) to opioid drugs (prescription or illegal) who have received an oral transmucosal (used under the tongue or inside the cheek) buprenorphine-containing medicine at a dose that controls withdrawal symptoms for at least 7 days. SUBLOCADE is part of a complete treatment plan that should include counseling.

SELECT IMPORTANT SAFETY INFORMATION
Because of the serious risk of potential harm or death from self-injecting SUBLOCADE into a vein (intravenously), it is only available through a restricted program called the SUBLOCADE REMS Program.

· SUBLOCADE is not available in retail pharmacies.

· Your SUBLOCADE injection will only be given to you by a certified healthcare provider.

See additional Important Safety Information and Medication Guide at www.sublocade.com.

[SPEECH]
SUBLOCADE is a prescription medicine used to treat adults with moderate to severe addiction to opioid drugs who have received an oral transmucosal buprenorphine-containing medicine at a dose that controls withdrawal symptoms for at least 7 days. SUBLOCADE is part of a complete treatment plan that should include counseling.

Because of the serious risk of potential harm or death from self-injecting SUBLOCADE into a vein, it is only available through a restricted program called the SUBLOCADE REMS Program.

SUBLOCADE is not available in retail pharmacies.

Your SUBLOCADE injection will only be given to you by a certified healthcare provider.

See additional Important Safety Information and Medication Guide at sublocade.com.

[DESCRIPTION]
Cut to overhead shot of Michael opening his book and flipping to the page about his childhood.

On-screen text:
Michael was paid by Indivior to share his experience with SUBLOCADE.

[SPEECH]
I grew up in a very small town. Very rural. Very early on it was clear that I struggled with attention stuff, like ADHD.

[DESCRIPTION]
Zoom into the image of Michael's childhood home.

[SPEECH]
And yeah, I was convinced that there was just something deeply wrong with me.

[DESCRIPTION]
Cut to diner scene. An overhead shot of a coffee cup at a diner booth.

On-screen text:
I don’t have willpower

[SPEECH]
That was my internal monologue, was that I just don’t—I don't have willpower.

[DESCRIPTION]
A birds-eye view of New York City buildings.

[SPEECH]
Years later, I was living with some friends in the city in some Upper East Side apartment.

[DESCRIPTION]
A scene depicting Michael's New York City apartment.

[SPEECH]
And they had a weed dealer. I asked the guy, ‘Hey, do you sell anything other than weed?’ And yeah, he sold, um, you know, oxycodone.

[DESCRIPTION]
Michael speaking from a diner booth.

On-screen text:
Sundays were oxycodone days

[SPEECH]
I wasn't a full-blown addict right away, but I also wasn't like taking 2 just to take a load off and then didn't think about it for another 2 weeks. It was suddenly my Sundays were oxycodone days.

[DESCRIPTION]
Michael flips the page in his book to the scene of his active addiction. Zoom in on the dark cityscape in Michael’s book and the illustration of him texting with “please stop” scribbled multiple times on the page.

[SPEECH]
It got to a point where it felt like I split into 2 people in some ways. As I was texting my dealer, I was saying out loud to myself, ‘Don't do this. Please stop. Don't do this,’ but it was truly like there was another person in me.

[DESCRIPTION]
A first-person point of view of a gurney being wheeled into a hospital entrance and down hallway begins, then cuts to Michael speaking from a diner booth, then back to the gurney scene.

[SPEECH]
I had overdosed, and I had been lying on my leg, cutting off circulation to it. I was in really excruciating nerve pain. And I was hospitalized.

[DESCRIPTION]
The gurney scene cuts to an overhead view of a snowy suburban neighborhood, then cuts back to Michael speaking from a diner booth, then back to him turning the page in his book.

On-screen text:
My family had to give me opioids for pain

[SPEECH]
Then, eventually, it was time for me to go home to my family. My poor shell-shocked, terrified, family has to give me opioids for the pain.

[DESCRIPTION]
Michael reads from a spread in his book which then zooms in on various elements of the page.

[SPEECH]
I went into their room, found the key, and started immediately stealing my prescription. I took all of the fentanyl that was left. They took me to the emergency room and I started OD’ing again.

[DESCRIPTION]
A circle of chairs set up for a group counseling session. Cut to Michael speaking from a diner booth.

On-screen text:
I started daily oral therapy

[SPEECH]
I was there overnight, and then I went to detox. While I was there, I was given a daily medication I was told would—would help. And I at that point, I was ready to do anything.

[DESCRIPTION]
Handwritten SUBLOCADE logo transforms into SUBLOCADE logo over Michael taking carrots out of a bag.

On-screen text:
Once-monthly SUBLOCADE logo

This video reflects Michael's experience while taking SUBLOCADE as part of his treatment plan. Individual results may vary.

[SPEECH]
I had a conversation with somebody talking about my experience with the daily medication, and he was telling me about SUBLOCADE.

[DESCRIPTION]
Cut to a side view of Michael in a kitchen, then to a close-up of him chopping carrots.

On-screen text:
Once a month

SUBLOCADE is administered by your provider once monthly.

[SPEECH]
This idea of having something that I could just go do once, not think about, seemed really exciting.

[DESCRIPTION]
Michael pours oil into a pan on a stovetop and adds chopped onions to it.

[SPEECH]
My experience with the daily medication, I had ups and downs. You still have to take something on a daily basis.

[DESCRIPTION]
Michael stirs sizzling chopped onions in a pan over a stovetop.

[SPEECH]
That experience reminded me of other times in my life where I've been dependent on stuff.

[DESCRIPTION]
Michael speaking from a diner booth.

On-screen text:
Opioids hijack your brain

[SPEECH]
We watched an informational video about how drugs, especially opioids, hijack your brain's dopamine system and yeah, it really made me appreciate a little bit how this was not a willpower thing for me.

[DESCRIPTION]
Michael adding cheese to 2 bowls of chili.

On-screen text:
Starting on SUBLOCADE

The most common side effects of SUBLOCADE® include: constipation, headache, nausea, injection site itching, vomiting, increase in liver enzymes, tiredness, and injection site pain.

[SPEECH]
The psychiatrist that I had there, we decided that I was going to do it. The first shot, like I was expecting it, so it actually wasn't too bad.

[DESCRIPTION]
A view of Michael chatting with someone while sitting at the dinner table.

On-screen text:
The most important thing is I don’t really think about it

[SPEECH]
The most important thing about SUBLOCADE, for me, is that I don't actually think about it most of the time, which sounds like a small thing, but it is a really important thing.

[DESCRIPTION]
Cut to a scanning view of tall trees outside with snow on the ground.

On-screen text:
Continuous medication that lasts all month

Blocks the rewarding effects of opioids*

*Blocked rewarding effects of an opioid in a 12-week study of 39 non-treatment-seeking adults.

[SPEECH]
I receive continuous medication throughout the month. SUBLOCADE blocks the rewarding effects of opioids. I knew I wouldn't feel the same effects if I use now.

[DESCRIPTION]
Overhead view of Michael grabbing a cup of coffee and lifting it. Cut to a side view of him taking a sip of coffee and looking toward the window.

[SPEECH]
I got a great therapist. Of course, continue to do, you know, recovery meetings, which are still a really important part of my life. Found a couple of really wonderful people who are really thoughtful, and see me as a human being.

[DESCRIPTION]
Michael speaking from the diner booth.

On-screen text:
Focus on how I can get better

[SPEECH]
As a person in recovery, there’s a lot of time that you spend stuck obsessing about drugs. Because of SUBLOCADE, I can focus on how I can get better.

[DESCRIPTION]
Michael comes into frame, riding a bicycle past a wooded area. Cut to close-up shot of Michael.

On-screen text:
It’s not a willpower battle anymore

[SPEECH]
It's not a willpower battle anymore. All of these tools that I've started to learn, like, present themselves one after another.

[DESCRIPTION]
Cut to Michael's book, where we see his story progress into his recovery.

[SPEECH]
Like, the way I feel about myself has honestly completely changed.

[DESCRIPTION]
Michael looking at the last spread of his book.

[SPEECH]
There's this expression that people say in recovery, ‘I hope you have a slow recovery.’ SUBLOCADE has been a big part of that. The point is, I want to keep learning my whole life and growing. It's gradual and that's okay.

[DESCRIPTION]
Overhead shot of Michael closing his book. Cut to on-screen text on blue background.

On-screen text:
Let’s talk more openly about recovery.

The opioid crisis affects us all. If you or someone you know is struggling with opioid addiction, visit SUBLOCADE.com/provider to find a doctor near you.

INDIVIOR logo

[END OF TRANSCRIPT]

P-BAG-US-01532